R-GNE-140
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2003234-63-5 | Cat. No. | BCP20732 |
| Name | R-GNE-140 | ||
| Synonyms | GNE-140;(R)-GNE-140; GNE 140; GNE140; | ||
| SMILES | C1COCCN1C2=CC=C(C=C2)C3(CC(=C(C(=O)N3)SC4=CC=CC=C4Cl)O)C5=CSC=C5 | ||
| Chemical Name | |||
| Formula | C25H23ClN2O3S2 | M. Wt | 499.04 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | (R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively；(R)-GNE-140 is 18-fold more potent than S enantiomer. IC50 & Target: IC50: 3 nM (LDHA), 5 nM (LDHB) | ||
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