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Decitabine Chemical Structure

Decitabine

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP02870CAS No. ：2353-33-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 2353-33-5 Cat. No. BCP02870
Name Decitabine
Synonyms 5-Aza-2'-deoxycytidine;5-AZA-CdR;5-Azadeoxycytidine;NSC 127716;NSC-127716;NSC127716;Dacogen;DAC;
SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O
Chemical Name
Formula C8H12N4O4 M. Wt 228.21
Purity 98% Storage Store at 4-8°C
Description Decitabine (NSC 127716; Dacogen; DAC)is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.
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H-NMR HPLC
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