HaloPROTAC-E New
Data Sheet
For research use only. Not for human use.
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|---|---|---|---|
| 10.00 mg | Get quote | In-stock | Quotation Inquiry |
| 25.00 mg | Get quote | In-stock | Quotation Inquiry |
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| CAS No. | 2365478-58-4 | Cat. No. | BCP44601 |
| Name | HaloPROTAC-E | ||
| Synonyms | |||
| SMILES | CC1=C(SC=N1)C2=CC(=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)C4(CC4)C#N)O)OCCOCCOCCOCCCCCCCl | ||
| Chemical Name | |||
| Formula | C39H56ClN5O8S | M. Wt | 790.41 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded. | ||
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