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Methylprednisolone sodium succinate Chemical Structure

Methylprednisolone sodium succinate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP11883CAS No. :2375-03-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2375-03-3 Cat. No. BCP11883
Name Methylprednisolone sodium succinate
Synonyms 6 alpha-Methylprednisolone Sodium Hemisuccinate;6α-Methylprednisolone 21-hemisuccinate sodium salt;
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
Chemical Name
Formula C26H33NaO8 M. Wt 496.53
Purity 98% Storage Store at 4-8°C
Description Methylprednisolone Sodium Succinate is the sodium succinate salt of a synthetic glucocorticoid receptor agonist with immunosuppressive and anti-inflammatory effects. Methylprednisolone sodium succinate is converted into active prednisolone in the body, which activates glucocorticoid receptor mediated gene expression. This includes inducing synthesis of anti-inflammatory protein IkappaB-alpha and inhibiting synthesis of nuclear factor kappaB (NF-kappaB). As a result, proinflammatory cytokine production such as IL-1, IL-2 and IL-6 is down-regulated and cytotoxic T-lymphocyte activation is inhibited. Therefore, an overall reduction in chronic inflammation and autoimmune reactions may be achieved.
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