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Dapivirine Chemical Structure

Dapivirine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06491CAS No. :244767-67-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 244767-67-7 Cat. No. BCP06491
Name Dapivirine
Synonyms TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681;
SMILES CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C
Chemical Name
Formula C20H19N5 M. Wt 329.4
Purity 98% Storage Store at 4-8°C
Description Dapivirine, also known as TMC120, is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission.
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