Luseogliflozin

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP20937CAS No. ：898537-18-3Purity：98%

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Chemical Properties&Biological Activity

CAS No.	898537-18-3	Cat. No.	BCP20937
Name	Luseogliflozin
Synonyms	TS-71; TS 71; TS71; TS-071; TS 071; TS071;
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=C(C(=C2)C3C(C(C(C(S3)CO)O)O)O)OC)C
Chemical Name
Formula	C23H30O6S	M. Wt	434.54
Purity	98%	Storage	Store at 4-8°C
Description	Luseogliflozin, also known as TS-71 and TS-071, is a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2 inhibitor). Luseogliflozin improves glycaemic control assessed by continuous glucose monitoring even on a low-carbohydrate diet. Luseogliflozin competitively inhibited human SGLT2 (hSGLT2)-mediated glucose uptake with a Ki value of 1.10 nM. In the absence of glucose, [(3)H]-luseogliflozin exhibited a high affinity for hSGLT2 with a Kd value of 1.3 nM.

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