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CAS No. | 110351-92-3 | Cat. No. | BCP41819 |
Name | (R)-Camptothecin | ||
Synonyms | 20R-Camptothecin;(R)-(-)-Camptothecin; | ||
SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O | ||
Chemical Name | |||
Formula | C20H16N2O4 | M. Wt | 348.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (R)-(-)-Camptothecin is an alkaloid that has been used for the treatment of cancer. (R)-(-)-Camptothecin binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. |
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