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Enarodustat Chemical Structure

Enarodustat

Data Sheet For research use only. Not for human use.
Cat. No. :BCP39690CAS No. :1262132-81-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1262132-81-9 Cat. No. BCP39690
Name Enarodustat
Synonyms JTZ-951; JTZ 951; JTZ951;
SMILES C1=CC=C(C=C1)CCC2=CC(=O)C(=C3N2NC=N3)C(=O)NCC(=O)O
Chemical Name
Formula C17H16N4O4 M. Wt 340.33
Purity 98% Storage Store at 4-8°C
Description Enarodustat, also known as JTZ-951, is a prolyl hydroxylase inhibitor. JTZ-951 (enarodustat) stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor. Enarodustat increases endogenous erythropoietin levels in the treatment of anemia associated with chronic kidney disease (CKD). JTZ-951 induces erythropoiesis without affecting VEGF function. JTZ-951 may be a new oral candidate that increases and maintains hemoglobin concentrations in renal anemia patients.
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