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PT2399 Chemical Structure

PT2399

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25901CAS No. :1672662-14-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1672662-14-4 Cat. No. BCP25901
Name PT2399
Synonyms PT-2399; PT 2399;
SMILES C1C2=C(C=CC(=C2C(C1(F)F)O)S(=O)(=O)C(F)F)OC3=CC(=CC(=C3)C#N)F
Chemical Name
Formula C17H10F5NO4S M. Wt 419.32
Purity 98% Storage Store at 4-8°C
Description PT2399 is a first-in-class, orally available, small molecule inhibitor of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β. Preclinical and clinical data indicate that PT2399 is effective in blocking cancer cell growth, proliferation, and tumor angiogenesis characteristic in ccRCC.
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