Pitstop2 New
Data Sheet
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| CAS No. | 1332879-52-3 | Cat. No. | BCP48928 |
| Name | Pitstop2 | ||
| Synonyms | Clathrin-IN-1;Pitstop 2; | ||
| SMILES | C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)N=C3NC(=O)C(=CC4=CC=C(C=C4)Br)S3 | ||
| Chemical Name | |||
| Formula | C20H13BrN2O3S2 | M. Wt | 473.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pitstop2 is a selective clathrin-mediated endocytosis (CME) inhibitor. Clathrin-IN-1 selectively inhibits amphiphysin association of clathrin terminal domain (TD) with an IC50 value of 12 μM. Clathrin-IN-1 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling. | ||
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