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BIT225 Chemical Structure

BIT225

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43946CAS No. :917909-71-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 917909-71-8 Cat. No. BCP43946
Name BIT225
Synonyms BIT-225;BIT 225;
SMILES CN1C=C(C=N1)C2=CC=CC3=C2C=CC(=C3)C(=O)N=C(N)N
Chemical Name
Formula C16H15N5O M. Wt 293.32
Purity 98% Storage Store at 4-8°C
Description BIT225, a novel acyl-guanidine, is a novel antiviral drug that blocks Vpu ion channel activity and has anti-HIV-1 activity in vitro. The antiviral effect of BIT225 is most pronounced in cells of the myeloid lineage. With infected circulating monocytes and tissue-resident macrophages representing a key cellular reservoir of HIV-1, BIT225 has a potential role in the eradication of the virus from the host.
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