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RO 9021 Chemical Structure

RO 9021

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP17963CAS No. ：1446790-62-0Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1446790-62-0 Cat. No. BCP17963
Name RO 9021
Synonyms RO-9021;RO9021;
SMILES
Chemical Name
Formula C18H25N7O M. Wt 355.44
Purity 98% Storage Store at 4-8°C
Description RO9021 is an oral, ATP-competative and selective inhibitor of spleen tyrosine kinase (SYK). RO-9021 potently inhibited SYK kinase activity with an average IC50 of 5.6 nM. RO-9021 is a highly selective SYK inhibitor with low S-scores of 0.003 for S(99) and 0.015 for S(90), indicating that SYK is the only kinase with 99% competition with RO-9021 (1 uM) in a total of 392 tested kinases.
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