DC-Cholesterol HCl New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 166023-21-8 | Cat. No. | BCP44901 |
| Name | DC-Cholesterol HCl | ||
| Synonyms | DC Cholesterol; | ||
| SMILES | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)NCCN(C)C)C)C.Cl | ||
| Chemical Name | |||
| Formula | C32H56N2O2.HCl | M. Wt | 537.26 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE, has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice. | ||
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