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Namitecan Chemical Structure

Namitecan

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP36777CAS No. ：372105-27-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 372105-27-6 Cat. No. BCP36777
Name Namitecan
Synonyms ST-1968; ST 1968; ST1968;
SMILES CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)C=NOCCN)O
Chemical Name
Formula C23H22N4O5 M. Wt 434.45
Purity 98% Storage Store at 4-8°C
Description Namitecan, also known as ST-1968, is a new water-soluble camptothecin analogue which showed high antitumor activity in preclinical models. ST1968 exhibited an impressive activity against several tumors including models of ovarian and colon carcinoma in which a high rate of cures was observed. t ST1968 was able to overcome the most relevant mechanisms associated with the development of topotecan resistance (i.e., slow proliferation and target downregulation) owing to its peculiar pharmacokinetic behaviour.
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