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CAS No. | 37854-59-4 | Cat. No. | BCP43382 |
Name | Ro 08-2750 | ||
Synonyms | Ro 082750; | ||
SMILES | CC1=CC2=C(C=C1C=O)N(C3=NC(=O)NC(=O)C3=N2)C | ||
Chemical Name | |||
Formula | C13H10N4O3 | M. Wt | 270.24 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. |
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