FOXY-5 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 881188-51-8 | Cat. No. | BCP43701 |
| Name | FOXY-5 | ||
| Synonyms | Foxy 5; Foxy5; | ||
| SMILES | CC(C)CC(C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CS)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC=O | ||
| Chemical Name | |||
| Formula | C26H42N6O12S2 | M. Wt | 694.77 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | FOXY-5 is a wnt signalling pathway modulator potentially forthe treatment of metastatic breast cancer, prostate cancer and colorectal cancer. In vitro analyses revealed that both recombinant Wnt-5a and the Wnt-5a-derived Foxy-5 peptide impaired migration and invasion without affecting apoptosis or proliferation of 4T1 breast cancer cells. The in vivo experiments show that i.p. injections of Foxy-5 inhibited metastasis of inoculated 4T1 breast cancer cells from the mammary fat pad to the lungs and liver by 70% to 90%. | ||
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