PTC299 New
Data Sheet
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| CAS No. | 1256565-36-2 | Cat. No. | BCP32869 |
| Name | PTC299 | ||
| Synonyms | PTC-299;PTC 299; | ||
| SMILES | COC1=CC=C(C=C1)C2C3=C(CCN2C(=O)OC4=CC=C(C=C4)Cl)C5=C(N3)C=CC(=C5)Cl | ||
| Chemical Name | |||
| Formula | C25H20Cl2N2O3 | M. Wt | 467.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PTC299 is a potent, orally bioavailable VEGFA inhibitor, targets dihydroorotate dehydrogenase (DHODH), resulting in cell growth inhibition and differentiation in leukemias, including acute myeloid leukemia, linking DHODH regulation and stress-induced VEGFA and angiogenesis. | ||
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