THPP-1 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1257051-63-0 | Cat. No. | BCP37557 |
| Name | THPP-1 | ||
| Synonyms | |||
| SMILES | COCCOC1=NC(=NC2=C1CN(CC2)C(=O)C3=C4C=CC=CN4C=N3)C5=CN=C(C=C5)Cl | ||
| Chemical Name | |||
| Formula | C23H21ClN6O3 | M. Wt | 464.91 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species. | ||
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