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DSR-141562 Chemical Structure

DSR-141562

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34050CAS No. :2007975-22-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2007975-22-4 Cat. No. BCP34050
Name DSR-141562
Synonyms DSR141562;DSR 141562;
SMILES CN1C(=O)C2=CN=C(N2N=C1OCC3CCC(CC3)C(F)(F)F)C4CCOCC4
Chemical Name
Formula C19H25F3N4O3 M. Wt 414.42
Purity 98% Storage Store at 4-8°C
Description DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.
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