Zaprinast New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 37762-06-4 | Cat. No. | BCP38400 |
| Name | Zaprinast | ||
| Synonyms | |||
| SMILES | CCCOC1=CC=CC=C1C2=NC3=NNN=C3C(=O)N2 | ||
| Chemical Name | |||
| Formula | C13H13N5O2 | M. Wt | 271.27 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Zaprinast is a cyclic-GMP phosphodiesterase inhibitor with selectivity for PDE6, 5, 11 and 9 (IC50 = 0.15, 0.76, 12.0 and 29.0 μM, respectively). C-GMP acts as a mediator of signal transduction that relaxes vascular smooth muscles and increases blood flow. Therefore zaprinast exhibits vasodilating, relaxant, and diuretic effects. Zaprinast also acts as a putative GPR35 agonist. | ||
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