Zandelisib New
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS No. | 1401436-95-0 | Cat. No. | BCP36800 |
Name | Zandelisib | ||
Synonyms | PWT143; PWT-143; PWT 143; ME-401; ME401; ME 401; | ||
SMILES | CC(C)(CC1=CC=CC=C1C2CCN(CC2)C)NC3=NC(=NC(=N3)N4CCOCC4)N5C6=CC=CC=C6N=C5C(F)F | ||
Chemical Name | |||
Formula | C31H38F2N8O | M. Wt | 576.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Zandelisib, also known as PWT143 and ME-401, is an orally bioavailable inhibitor of the delta isoform of phosphatidylinositide 3-kinase (PI3K), with potential antineoplastic activity. Upon oral administration, PI3K-delta inhibitor PWT143 selectively inhibits the delta isoform of PI3K and prevents the activation of the PI3K/AKT signaling pathway. This both decreases proliferation and induces cell death in PI3K-delta-overexpressing tumor cells. PI3K-delta plays a key role in the proliferation and survival of hematologic cancer cells. The targeted inhibition of PI3K-delta is designed to preserve PI3K signaling in normal, non-neoplastic cells. PI3K, an enzyme often overexpressed in cancer cells, plays a crucial role in tumor cell regulation and survival. |
Recommend Products
More >-
-
PI3K/mTOR Inhibitor-2
Cat. No.:BCP48401
No.:1848242-58-9
Product Details -
-
Disitertide
Cat. No.:BCP46789
No.:272105-42-7
Product Details -
IHMT-PI3Kδ-372
Cat. No.:BCP46775
No.:2429889-62-1
Product Details -
Gilmelisib
Cat. No.:BCP46378
No.:1845777-61-8
Product Details -
-
ETP-45658
Cat. No.:BCP45165
No.:1198357-79-7
Product Details -
-
Panulisib
Cat. No.:BCP44105
No.:1356033-60-7
Product Details -
Parsaclisib hydrochloride
Cat. No.:BCP42656
No.:1995889-48-9
Product Details -
-
-
-
Nemiralisib
Cat. No.:BCP38658
No.:1254036-71-9
Product Details -
TGR1202 racemate
Cat. No.:BCP24685
No.:1532533-65-5
Product Details -
Umbralisib tosylate
Cat. No.:BCP24684
No.:1532533-72-4
Product Details -
Umbralisib R-enantiomer
Cat. No.:BCP24683
No.:1532533-69-9
Product Details -
Umbralisib sulfate
Cat. No.:BCP24681
No.:1532533-75-7
Product Details -
GSK2292767
Cat. No.:BCP24323
No.:1254036-66-2
Product Details
Tags:Zandelisib supplier,Zandelisib purchase,Zandelisib manufacturer,Zandelisib distributor,Zandelisib cost,Zandelisib buy,Zandelisib for sale