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LY294002 Chemical Structure

LY294002

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP00195CAS No. ：154447-36-6Purity：98%
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  • Publications Citing of Biochempartner's LY294002
Indian J Pharm Sci 2022;84(2):493-500
  • Chemical Properties&Biological Activity
CAS No. 154447-36-6 Cat. No. BCP00195
Name LY294002
Synonyms NSC 697286; SF 1101; LY 294002; LY-294002; NSC-697286; SF-1101; NSC697286; SF1101;
SMILES
Chemical Name
Formula C19H17NO3 M. Wt 307.34
Purity 98% Storage Store at 4-8°C
Description LY294002 inactivates Akt/PKB, consequently inhibiting cell proliferation and inducing apoptosis. LY294002 demonstrates a remarkable growth-inhibitory and apoptosis-inducing effect in these colon cancer cell lines, with decreased expression of phosphorylated Akt (Ser473). LY294002 induces marked nuclear pyknosis and diminished cytoplasmic volume in the tumor cells. Thus, LY294002 markedly inhibits ovarian cancer cell proliferation in vitro. LY294002 induces specific G1 arrest in cell growth, lead
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H-NMR HPLC
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