Home   >  
Cell Cycle/DNA Damage
  • PI3K/Akt/mTOR
  >  
ATM/ATR
  >   AZD1390
AZD1390 Chemical Structure

AZD1390

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28994CAS No. :2089288-03-7Purity:98%
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • Chemical Properties&Biological Activity
CAS No. 2089288-03-7 Cat. No. BCP28994
Name AZD1390
Synonyms AZD-1390; AZD 1390;
SMILES O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C (OCCCN5CCCCC5)N=C4)=C(F)C=C3N=C2
Chemical Name
Formula C27H32FN5O2 M. Wt 477.58
Purity 98% Storage Store at 4-8°C
Description AZD1390 is a potent and selective ATM inhibitor with the ability to cross the blood-brain barrier suitable for the treatment of intracranial malignancies.AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50 = 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. AZD1390 displays excellent oral bioavailability in preclinical species (66% in rat and 74% in dog), is not a substrate for human efflux transporters, and has been shown to efficiently cross the BBB in non-human primate PET studies.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:AZD1390 supplier,AZD1390 purchase,AZD1390 manufacturer,AZD1390 distributor,AZD1390 cost,AZD1390 buy,AZD1390 for sale

0086-13720134139