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RO5126766 Chemical Structure

RO5126766

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP21067CAS No. ：946128-88-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 946128-88-7 Cat. No. BCP21067
Name RO5126766
Synonyms RO 5126766; RO5126766; CH5126766; CH5126766; CH 5126766;
SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
Chemical Name
Formula C21H18FN5O5S M. Wt 471.46
Purity 98% Storage Store at 4-8°C
Description RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity. Raf/MEK dual kinase Inhibitor RO5126766 specifically inhibits the kinase activities of Raf and MEK, resulting in the inhibition of of target gene transcription that promotes malignant transformation of cells. Both Raf and MEK are serine/threonine-specific kinases that respond to extracellular stimuli, such as mitogens, and are involved in the regulation of cellular processes, such as gene expression, mitosis, differentiation, and apoptosis.
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