Home   >  
MAPK Pathway
  >  
MEK/ERK
  >   ASN007
ASN007 Chemical Structure

ASN007

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP48479CAS No. ：2055597-12-9Purity：98%
chem_1Get Quotation Now
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Chemical Properties&Biological Activity
CAS No. 2055597-12-9 Cat. No. BCP48479
Related Products 2055597-39-0（ASN007 benzenesulfonate）
Name ASN007
Synonyms ASN-007; ASN 007;Erk-IN-3;
SMILES CC1=CN=C(N=C1N2C=C(N=C2)C(=O)NC(CN)C3=CC(=CC(=C3)Cl)F)NC4CCOCC4
Chemical Name
Formula C22H25ClFN7O2 M. Wt 473.93
Purity 98% Storage Store at 4-8°C
Description ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models. with low single-digit nM IC50 values. ASN007 showed a slow dissociation rate (long target residence time) as compared to several other known ERK inhibitors. In mechanistic cell-based assays, ASN007 inhibited the phosphorylation of ERK1/2 substrates such as RSK1, FRA1, and Elk1 in various cell lines. ASN007 showed single-digit nanomolar antiproliferative activity that was selective for MAPK-pathway dependent cancer cell lines.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:ASN007 supplier,ASN007 purchase,ASN007 manufacturer,ASN007 distributor,ASN007 cost,ASN007 buy,ASN007 for sale

0086-13720134139