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ETP-46464 Chemical Structure

ETP-46464

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08061CAS No. :1345675-02-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1345675-02-6 Cat. No. BCP08061
Name ETP-46464
Synonyms ETP 46464; ETP46464;
SMILES
Chemical Name
Formula C30H22N4O2 M. Wt 470.52
Purity 98% Storage Store at 4-8°C
Description ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα, and ATM (IC50 = 0.6, 14, 36, 170, and 545 nM, respectively) and preferentially suppresses radiation-induced cellular ATR activity (>90% at 500 nM) over ATM or DNA-PK activity (IC50 > 5 uM) in
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