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IκB/IKK

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IκB/IKK

Chemical Structure Cat. No. Product Name CAS No.
TBK1/IKKε-IN-5 Chemical Structure
 BCP43331 TBK1/IKKε-IN-5 1893397-65-3
TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively.
ACHP Chemical Structure
 BCP41504 ACHP 406208-42-2
ACHP is an IκB kinase inhibitor that inhibits DNA binding activity of NF-κB, blocks NF-κB pathway in multiple myeloma cell lines, and induces cell growth arrest and apoptosis.
NF-κB-IN-1 Chemical Structure
 BCP40303 NF-κB-IN-1 1227098-15-8
NF-κB-IN-1, a 4-arylidene crucumin analogue, is a potent NF-κB signaling pathway inhibitor.
Chemical Structure
IKK-2 Inhibitor VIII Chemical Structure
 BCP21394 IKK-2 Inhibitor VIII 406209-26-5
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
INH14 Chemical Structure
 BCP31056 INH14 200134-22-1
INH14 is an inhibitor of the IKKα/β-dependent TLR inflammatory response.
WS3 Chemical Structure
 BCP10968 WS3 1421227-52-2
WS3 is a novel small molecule that promotes β cell proliferation with EC50 of 28 nM(induced R7T1 proliferation).
Acetyl-trans-resveratrol Chemical Structure
 BCP24098 Acetyl-trans-resveratrol 42206-94-0
Triacetyl resveratrol is Resveratrol prodrug.
Wedelolactone Chemical Structure
 BCP19859 Wedelolactone 524-12-9
Wedelolactone is isolated and purified from the herbs of Eclipta prostrata.
Bay 11-7821 Chemical Structure
 BCP06798 Bay 11-7821 19542-67-7
BAY 11-7082 is a NF-κB inhibitor which decreases NF-κB by inhibiting TNF-α-induced phosphorylation of IκB-α. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50s of 0.19 μM and 0.96 μM, respectively.
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