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NFκB

Chemical Structure Cat. No. Product Name CAS No.
WAY-204688 Chemical Structure
BCP46376 WAY-204688 796854-35-8
WAY-204688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50: 122 ± 30 nM for NF-κB-luciferase in HAECT-1 cells).
Nrf2 activator-1 Chemical Structure
BCP45478 Nrf2 activator-1 2230697-41-1
Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2).
SP-8356 Chemical Structure
BCP45208 SP-8356 1454885-45-0
SP-8356 an anti-inflammatory synthetic verbenone derivative, is a potent, orally active cluster of differentiation 147 (CD147) inhibitor.
N-Acetyl-cysteine Chemical Structure
BCP45078 N-Acetyl-cysteine 616-91-1
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results. Acetylcysteine was granted FDA approval on 14 September 1963.
B022 Chemical Structure
BCP45058 B022 1202764-53-1
B022 is a novel inhibitor of NF-kappaB-inducing kinase (NIK), protecting liver from toxin-induced inflammation, oxidative stress, and injury.
MLT-943 Chemical Structure
BCP44966 MLT-943 1832576-04-1
MLT-943 is a novel potent and selective MALT1 protease inhibitor.
Hoipin-1 Chemical Structure
BCP43940 Hoipin-1 JTP-0819958
HOIPIN-1 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM.
Lipoteichoic acid Chemical Structure
BCP43680 Lipoteichoic acid 56411-57-5
Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways, also used as adjuvant.
JNJ-67856633 Chemical Structure
BCP43413 JNJ-67856633 2230273-76-2
JNJ-67856633 is novel, first-in-Class MALT1 Protease Inhibitor for the Treatment of B Cell Lymphomas.
IT-603 Chemical Structure
BCP43206 IT-603 292168-90-2
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
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