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NF κB

Chemical Structure Cat. No. Product Name CAS No.
Hoipin-1 Chemical Structure
 BCP43940 Hoipin-1 JTP-0819958
HOIPIN-1 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM.
Lipoteichoic acid Chemical Structure
 BCP43680 Lipoteichoic acid 56411-57-5
Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways, also used as adjuvant.
IT-603 Chemical Structure
 BCP43206 IT-603 292168-90-2
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
UCB-9260 Chemical Structure
 BCP40717 UCB-9260 1515888-53-5
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer.
NIK SMI1 Chemical Structure
 BCP38023 NIK SMI1 1660114-31-7
NIK SMI1 is a highly selective and potent NF-κB-inducing kinase (NIK) inhibitor.
SEMBL Chemical Structure
 BCP38022 SEMBL 1443448-82-5
SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65.
Urolithin B Chemical Structure
 BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
DHMEQ Chemical Structure
 BCP35164 DHMEQ 287194-40-5
DHMEQ is a potent NF-κB inhibitor.
Dihydrobigelovin Chemical Structure
 BCP34452 Dihydrobigelovin 54999-07-4
Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica. Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.
Tyrosol Chemical Structure
 BCP34277 Tyrosol 501-94-0
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
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