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NF κB

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NF κB

Chemical Structure Cat. No. Product Name CAS No.
Sodium salicylate Chemical Structure
BCP47031 Sodium salicylate 54-21-7
Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
Sappanone A Chemical Structure
BCP46467 Sappanone A 102067-84-5
Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma.
SM-7368 Chemical Structure
BCP46452 SM-7368 380623-76-7
SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner. SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line.
NDMC101 Chemical Structure
BCP46451 NDMC101 1308631-40-4
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
WAY-204688 Chemical Structure
BCP46376 WAY-204688 796854-35-8
WAY-204688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50: 122 ± 30 nM for NF-κB-luciferase in HAECT-1 cells).
SP-8356 Chemical Structure
BCP45208 SP-8356 1454885-45-0
SP-8356 an anti-inflammatory synthetic verbenone derivative, is a potent, orally active cluster of differentiation 147 (CD147) inhibitor.
N-Acetyl-cysteine Chemical Structure
BCP45078 N-Acetyl-cysteine 616-91-1
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results. Acetylcysteine was granted FDA approval on 14 September 1963.
B022 Chemical Structure
BCP45058 B022 1202764-53-1
B022 is a novel inhibitor of NF-kappaB-inducing kinase (NIK), protecting liver from toxin-induced inflammation, oxidative stress, and injury.
Hoipin-1 Chemical Structure
BCP43940 Hoipin-1 JTP-0819958
HOIPIN-1 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM.
Lipoteichoic acid Chemical Structure
BCP43680 Lipoteichoic acid 56411-57-5
Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways, also used as adjuvant.
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