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FXR

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FXR

Chemical Structure Cat. No. Product Name CAS No.
ASC-42 Chemical Structure
 BCP49481 ASC-42 ASC-42
ASC 42 is a selective, non-steroidal, potent Farnesoid X Receptor (FXR) agonist.
MET-642 Chemical Structure
 BCP49382 MET-642 MET-642
MET 642 is a small molecule farnesoid X receptor (FXR) agonist.
Omesdafexor Chemical Structure
 BCP49254 Omesdafexor 2244440-85-3
Omesdafexor is a FXR agonist.
Fexarine Chemical Structure
 BCP24188 Fexarine 574013-67-5
Fexarine is a potent, selective farnesoid X receptor agonist.
Cilofexor tromethamine Chemical Structure
 BCP43200 Cilofexor tromethamine 2253764-93-9
Cilofexor is a farnesoid X receptor (FXR) agonist.
EDP-305 Chemical Structure
 BCP40718 EDP-305 1933507-63-1
EDP-305 is a novel and potent farnesoid X receptor (FXR) agonist, with no/minimal cross-reactivity to TGR5 or other nuclear receptors.
(Z)-Guggulsterone Chemical Structure
 BCP07472 (Z)-Guggulsterone 39025-23-5
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Vonafexor Chemical Structure
 BCP33693 Vonafexor 1192171-69-9
Vonafexor is a farnesoid X receptor agonist.
LY2562175 Chemical Structure
 BCP33226 LY2562175 1103500-20-4
LY2562175 is a potent and selective FXR agonist with an EC50 of 193 nM.
Sevelamer hydrochloride Chemical Structure
 BCP21176 Sevelamer hydrochloride 152751-57-0
Sevelamer Hcl is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
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