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Vistusertib

Cat. No. :BCP05748CAS No. :1009298-59-2Purity:98%
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Synonyms AZD 2014; AZD-2014; AZD2014
CAS Number 1009298-59-2
Purity 98%
M. Wt 462.54
Formula C25H30N6O3
Storage Store at 4-8°C
AZD2014 is a selective inhibitor of mTOR kinase. AZD2014 decreases p4EBP1 Thr37/46, inhibits the translation initiation complex and decreases overall protein synthesis. AZD2014 also inhibits the mTORC2 biomarkers pAKTSer473 and pNDRG1 Thr346. AZD2014 inhibits proliferation and induces cell death in breast cancer cell lines, including ER+ cell lines with acquired resistance to hormone therapy.

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