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XL413 Chemical Structure

XL413

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP20703CAS No. ：1169558-38-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1169558-38-6 Cat. No. BCP20703
Name XL413
Synonyms XL 413;XL-413;BMS 863233;BMS863233;BMS-863233;
SMILES
Chemical Name
Formula C14H12ClN3O2 M. Wt 289.72
Purity 98% Storage Store at 4-8°C
Description BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.
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