TAS-116 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1260533-36-5 | Cat. No. | BCP25132 |
| Name | TAS-116 | ||
| Synonyms | TAS116;TAS 116; Pimitespib; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C25H26N8O | M. Wt | 454.54 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | TAS-116 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) subtypes alpha and beta, with potential antineoplastic and chemo/radiosensitizing activities. TAS-116 specifically binds to and inhibits the activity of Hsp90 alpha and beta; this results in the proteasomal degradation of oncogenic client proteins, which inhibits client protein dependent-signaling, induces apoptosis, and inhibits the proliferation of cells overexpressing HSP90alpha/beta. | ||
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