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FR 122047 hydrochloride Chemical Structure

FR 122047 hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35730CAS No. :130717-51-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 130717-51-0 Cat. No. BCP35730
Name FR 122047 hydrochloride
Synonyms FR-122047 HCl; FR 122047 HCl; FR122047 HCl;
SMILES CN1CCN(CC1)C(=O)C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC.Cl
Chemical Name
Formula C23H26ClN3O3S M. Wt 459.99
Purity 98% Storage Store at 4-8°C
Description FR-122047 is a potent and selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.028 and 65 μM for COX-1 and COX-2 respectively). FR122047 treatment led to a distinct suppression of cell growth in MCF-7 cells. FR122047 may have an anti-cancer potential in breast cancer.
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