AM-92016 hydrochloride New
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CAS No. | 133229-11-5 | Cat. No. | BCP31856 |
Name | AM-92016 hydrochloride | ||
Synonyms | AM-92016 HCl; AM 92016 HCl; AM92016 HCl; AM92016 hydrochloride; | ||
SMILES | CN(CCC1=CC(=C(C=C1)Cl)Cl)CC(COC2=CC=C(C=C2)NS(=O)(=O)C)O.Cl | ||
Chemical Name | |||
Formula | C19H25Cl3N2O4S | M. Wt | 483.84 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK). AM-92016 is an oxypropanolamine analogue of sotalol, has been shown to possess Class III anti-arrhythmic properties in-vitro at concentrations showing 1000 times more potency than sotalol. AM 92016 exhibited proarrhythmic rather than antiarrhythmic activity when administered in-vivo to either guinea-pigs or pigs. |
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