WS6 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1421227-53-3 | Cat. No. | BCP10967 |
| Name | WS6 | ||
| Synonyms | WS-6;WS 6; | ||
| SMILES | CN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)CC3=CC=C(C=C3)OC4=NC=NC(=C4)NC(=O)C5CC5)C(F)(F)F | ||
| Chemical Name | |||
| Formula | C29H31F3N6O3 | M. Wt | 568.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | WS6 is a beta cell proliferation simulator. WS6 stimulates proliferation of both human beta and alpha cells while maintaining cellular viability and the beta cell differentiated phenotype. WS6 normalized blood glucose and induced concomitant increases in β cell proliferation and β cell number. Affinity pulldown and kinase profiling studies implicate Erb3 binding protein-1 and the IκB kinase pathway in the mechanism of action of WS6. WS6 may help increase human islet mass needed for successful treatment of diabetes. | ||
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