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Selegiline hydrochloride Chemical Structure

Selegiline hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP38874CAS No. :14611-52-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 14611-52-0 Cat. No. BCP38874
Name Selegiline hydrochloride
Synonyms Selegiline Hcl;
SMILES CC(CC1=CC=CC=C1)N(C)CC#C.Cl
Chemical Name
Formula C13H18ClN M. Wt 223.74
Purity 98% Storage Store at 4-8°C
Description Selegiline Hydrochloride is the hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkinsonian effect. As a selective monoamine oxidase (MAO) inhibitor, selegiline has the greatest affinity for type B MAO, found mainly in the brain. Selegiline is converted by MAO B to an active moiety, which binds irreversibly at the active site of the enzyme's cofactor FAD (flavin adenine dinucleotide) molecule. This prevents the oxidative deamination of catecholamines and serotonin by MAO B, and leads to an increase in these neurotransmitters' activities resulting in improved motor function. In addition, this agent may inhibit re-uptake of dopamine by the neuron and prolong dopamine activity.
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