Omaveloxolone New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1474034-05-3 | Cat. No. | BCP28609 |
| Name | Omaveloxolone | ||
| Synonyms | RTA408; RTA408; RTA-408;Nrf1-activator-1; | ||
| SMILES | CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)NC(=O)C(C)(F)F)C | ||
| Chemical Name | |||
| Formula | C33H44F2N2O3 | M. Wt | 554.71 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Omaveloxolone, also known as RTA-408, is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). | ||
Recommend Products
More >
-
Sappanone A
Cat. No.：BCP46467
No.：102067-84-5
Product Details -
Nrf2 activator-1
Cat. No.：BCP45478
No.：2230697-41-1
Product Details -
-
Arimoclomol
Cat. No.：BCP38425
No.：289893-25-0
Product Details -
Arimoclomol citrate
Cat. No.：BCP38424
No.：368860-21-3
Product Details -
Arimoclomol maleate
Cat. No.：BCP38423
No.：289893-26-1
Product Details -
-
-
4-Octyl Itaconate
Cat. No.：BCP31060
No.：3133-16-2
Product Details -
-
-
Dl-sulforaphane
Cat. No.：BCP19599
No.：4478-93-7
Product Details -
-
-
-
-
Ezetimibe Ketone
Cat. No.：BCP09273
No.：191330-56-0
Product Details -
-
-
Bardoxolone
Cat. No.：BCP04662
No.：218600-44-3
Product Details
Tags:Omaveloxolone supplier,Omaveloxolone purchase,Omaveloxolone manufacturer,Omaveloxolone distributor,Omaveloxolone cost,Omaveloxolone buy,Omaveloxolone for sale