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Branaplam Chemical Structure

Branaplam

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19909CAS No. :1562338-42-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1562338-42-4 Cat. No. BCP19909
Related Products 1562338-39-9(Branaplam hydrochloride)
Name Branaplam
Synonyms LMI-070;LMI070;LMI 070;NVS-SM1;
SMILES OC1=CC(C2=CNN=C2)=CC=C1C3=NN=C(OC4CC(C)(C)NC(C)(C)C4)C=C3.[H]Cl
Chemical Name
Formula C22H27N5O2 M. Wt 393.48
Purity 98% Storage Store at 4-8°C
Description Branaplam, also known as NVS-SM1 and LMI-070, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) .NVS-SM1 works by increasing the amount of functional SMN protein produced by the “back-up” gene, SMN2, through modifying its splicing.
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