ONC206 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1638178-87-6 | Cat. No. | BCP43713 |
| Name | ONC206 | ||
| Synonyms | ONC-206; ONC 206; | ||
| SMILES | C1CN(CC2=C1N3CCN=C3N(C2=O)CC4=C(C=C(C=C4)F)F)CC5=CC=CC=C5 | ||
| Chemical Name | |||
| Formula | C23H22F2N4O | M. Wt | 408.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ONC206 is a chemical analogue of ONC201. ONC206 is a benzyl-flurobenzyl imipridone that has highly potent activity in preclinical models of difficult-to-treat neuroendocrine tumors and sarcomas. ONC206 acts as a selective antagonist of DRD2 at nanomolar concentrations and has broad-spectrum anti-tumor activity. ONC206 may address tumor types where the properties of ONC201 do not permit for complete therapeutic engagement in vivo. | ||
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