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SN-011 Chemical Structure

SN-011

Data Sheet For research use only. Not for human use.
Cat. No. :BCP41129CAS No. :2249435-90-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2249435-90-1 Cat. No. BCP41129
Name SN-011
Synonyms SN011;SN 011;
SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)O)NS(=O)(=O)C4=CC=C(C=C4)F
Chemical Name
Formula C25H19FN2O4S M. Wt 462.49
Purity 98% Storage Store at 4-8°C
Description SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease.
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