Ac-FLTD-CMK New
Data Sheet
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| CAS No. | 2376255-48-8 | Cat. No. | BCP43135 |
| Name | Ac-FLTD-CMK | ||
| Synonyms | |||
| SMILES | CC(C)CC(C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)CCl)NC(=O)C(CC1=CC=CC=C1)NC(=O)C | ||
| Chemical Name | |||
| Formula | C26H37ClN4O8 | M. Wt | 569.05 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3. | ||
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