Apratastat New
Data Sheet
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| CAS No. | 287405-51-0 | Cat. No. | BCP27735 |
| Name | Apratastat | ||
| Synonyms | TMI-005; TMI005; TMI 005; XMT-1191; XMT 1191; XMT1191; | ||
| SMILES | CC1(C(N(CCS1)S(=O)(=O)C2=CC=C(C=C2)OCC#CCO)C(=O)NO)C | ||
| Chemical Name | |||
| Formula | C17H22N2O6S2 | M. Wt | 414.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Apratastat is a matrix metalloproteinase/tumour necrosis factor-α convertase (MMP/TACE) inhibitor for the treatment of rheumatoid arthritis. It inhibits secretion of soluble TNF-α and downregulates multiple MMPs, which is involved in cartilage destruction and bone erosions of RA. | ||
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