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U 18666A Chemical Structure

U 18666A

Data Sheet For research use only. Not for human use.
Cat. No. :BCP41254CAS No. :3039-71-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 3039-71-2 Cat. No. BCP41254
Name U 18666A
Synonyms U 18666A; U18666A; U 18666 A; U-18666-A; NSC-70801; NSC 70801; NSC70801;
SMILES CCN(CC)CCOC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4=O)C)C.Cl
Chemical Name
Formula C25H42ClNO2 M. Wt 424.06
Purity 98% Storage Store at 4-8°C
Description U 18666A is an inhibitor of cholesterol synthesis. It acts by inhibiting desmosterol Δ24-reductase. U18666A inhibits classical swine fever virus replication through interference with intracellular cholesterol trafficking. U18666A or other cholesterol transport inhibitor may be considered as the antiviral drug for the treatment of cats with FIP. U18666A accumulated intracellular free cholesterol in the culture of normal medium but not cholesterol-free medium. U18666A also induced reactive oxygen species (ROS) generation in normal medium but much less in cholesterol-free medium.
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