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SIB 1757 Chemical Structure

SIB 1757

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33033CAS No. :31993-01-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 31993-01-8 Cat. No. BCP33033
Name SIB 1757
Synonyms SIB-1757; SIB1757;
SMILES CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2
Chemical Name
Formula C12H11N3O M. Wt 213.24
Purity 98% Storage Store at 4-8°C
Description SIB-1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. SIB-1757 displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
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