Lurasidone
Data Sheet
For research use only. Not for human use.
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| CAS No. | 367514-87-2 | Cat. No. | BCP22902 |
| Name | Lurasidone | ||
| Synonyms | SM13496; SM-13496; SM 13496; SM13,496; SM-13,496; SM 13,496; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H36N4O2S | M. Wt | 492.68 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Lurasidone is a new atypical antipsychotic. I is also approved for the treatment of depressive episodes associated with bipolar I disorder (bipolar depression) in adults when used alone or in combination with lithium or valproate. Lurasidone acts as an antagonist of the following sites: α1-adrenergic receptor (Ki = 48 nM); α2A-adrenergic receptor (Ki = 1.6 nM); α2C-adrenergic receptor (Ki = 10.8 nM); D1 receptor (Ki = 262 nM); D2 receptor (Ki = 1.7 nM); 5-HT2A receptor (Ki = 2.0 nM); 5-HT2C receptor (Ki = 415 nM); 5-HT7 receptor (Ki = 0.5 nM). And as a partial agonist of the following sites: 5-HT1A receptor (Ki = 6.8 nM). (Source: http://en.wikipedia.org/wiki/Lurasidone). | ||
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