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3MA Chemical Structure

3MA

Cat. No. :BCP02452CAS No. :5142-23-4Purity:98%
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Synonyms 3-MA; 3-methyl-adenin;3-Methyladenine;Adenine, 3-methyl-;3-Methyl-3H-purin-6-amine;3-Methyl-6-am; 6-Amino-3-methylpurine
CAS Number 5142-23-4
Purity 98%
M. Wt 149.15
Formula C6H7N5
Storage Store at -20°C
Autophagy Inhibitor, 3-MA is a synthetic intermediate and a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis post serum/potassium deprivation. Autophagy Inhibitor, 3-MA is a class III PI 3-kinase inhibitor that displays distinctly different properties from the PI 3-kinase inhibitors LY 294002 and Wortmannin, in that treatment of cells with 3-MA results in specific redistribution of mannose 6-phosphate/insulin-like growth factor II receptor (MPR300), but does not cause the enlargement of late endosomal/lysosomal compartments.

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