Lenalidomide hemihydrate New
Data Sheet
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| CAS No. | 847871-99-2 | Cat. No. | BCP25399 |
| Name | Lenalidomide hemihydrate | ||
| Synonyms | CC-5013 hemihydrate;CC 5013 hemihydrate;CC5013 hemihydrate; | ||
| SMILES | C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N.C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N.O | ||
| Chemical Name | |||
| Formula | C26H28N6O7 | M. Wt | 536.55 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Lenalidomide hemihydrate, a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. | ||
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