SGI-1027
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1020149-73-8 | Cat. No. | BCP09928 |
| Name | SGI-1027 | ||
| Synonyms | SGI 1027;SGI1027; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C27H23N7O | M. Wt | 461.52 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SGI-1027, inhibits the activity of DNMT1, DNMT3A, and DNMT3B as well M. SssI with comparable IC(50) (6-13 micromol/L) by competing with S-adenosylmethionine in the methylation reaction. Treatment of different cancer cell lines with SGI-1027 resulted in selective degradation of DNMT1 with minimal or no effects on DNMT3A and DNMT3B. At a concentration of 2.5 to 5 micromol/L (similar to that of decitabine), complete degradation of DNMT1 protein was achieved within 24 h without significantly affecting its mRNA level. | ||
Recommend Products
More >
-
Bobcat339 hydrochloride
Cat. No.：BCP49654
No.：2436747-44-1
Product Details -
(R)-GSK-3685032
Cat. No.：BCP45844
No.：2170140-50-6
Product Details -
GSK3685032 TFA
Cat. No.：BCP45843
No.：GSK3685032TFA
Product Details -
GSK3685032
Cat. No.：BCP43733
No.：2170137-61-6
Product Details -
-
-
Bobcat339
Cat. No.：BCP31159
No.：2280037-51-4
Product Details -
Guadecitabine sodium
Cat. No.：BCP24636
No.：929904-85-8
Product Details -
Gamma-Oryzanol
Cat. No.：BCP13528
No.：11042-64-1
Product Details -
-
Guadecitabine
Cat. No.：BCP28067
No.：929901-49-5
Product Details -
-
-
5-Azacytidine
Cat. No.：BCP07496
No.：320-67-2
Product Details -
Lomeguatrib
Cat. No.：BCP07818
No.：192441-08-0
Product Details
Tags:SGI-1027 supplier,SGI-1027 purchase,SGI-1027 manufacturer,SGI-1027 distributor,SGI-1027 cost,SGI-1027 buy,SGI-1027 for sale